| KIDNEY FUNCTIONS |
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Urine Formation |
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Other Functions |
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| KIDNEY FILTERS AND PURIFIES BLOOD |
| Blood to be purified is passed through a haemofiltration element and a haemodialysis element in cascade and the ultrafiltrate output from the haemofiltration element is passed through a filter such as an activated carbon filter, preferably with uncoated activated carbon. The ultrafiltrate thus purified can then be used as a reinfusion solution to be readministered to the patient. |
- Function of the renal corpuscle (glomerulus and Bowman's capsule)
- Filtration rate based on differences in hydrostatic pressure and oncotic pressure on each side of the filtration membrane
- Hydrostatic pressure in glomerulus (capillaries) based on blood pressure
- Hydrostatic pressure in Bowman's capsule based on filtrate buildup
- Capillary hydrostatic pressure typically much higher than hydrostatic pressure in Bowman's capsule
- Protein can not cross filtration membrane normally
- As fluid leaves blood protein concentration increases in capillaries developing an oncotic pressure to retain some fluid in blood
- Protein normally not in filtrate or Bowman's capsule—no oncotic pressure
- Surface area available for filtration and filtration membrane permeability also affect filtration rate, but in normal kidney these are constant factors
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